裙带菜可溶性膳食纤维对小鼠脂质异常的影响
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裙带菜可溶性膳食纤维对小鼠脂质异常的影响(5000字)
摘 要：目的： 研究裙带菜可溶性膳食纤维对载脂蛋白E缺陷小鼠脂质异常的影响。方法： 40只小鼠分为4组(n=10): 对照组(C57BL/6J小鼠)；高脂模型组(载脂蛋白E缺陷小鼠)，膳食纤维低剂量组(5%)，膳食纤维高剂量组(10%)；经裙带菜可溶性膳食纤维处理8周后，检测血浆和肝脏脂类水平。结果： 裙带菜可溶性膳食纤维显著降低血浆和肝脏TG、TC、增加血浆HDL-C水平。结论：裙带菜可溶性膳食纤维能改善载脂蛋白E缺陷小鼠脂质异常。
关键词：裙带菜；可溶性膳食纤维；载脂蛋白E缺陷小鼠
THE EFFECT OF UNDARIA PINNATIFIDA DIETARY FIBER ON DYSLIPIDEMIA IN MICE
Abstract: Objective:To test the effect of Undaria pinnatifida soluble dietary fiber on dyslipidemia in apolipoprotein E deficient mice. Method:40 mice were divided into 4 groups (n=10): control group (C57BL/6J mice), high lipids group(apolipoprotein E deficient mice), low dose dietary fiber-treated group (5%), high dose dietary fiber -treated group(10%). After treatment of undaria pinnatifida soluble dietary fiber for 8 weeks, the contents of plasma and hepatic lipids was determined. Results:Undaria pinnatifida soluble dietary fiber treatment significantly decreased the levels of plasma and hepatic TC, TG, but significantly increased the plasma HDL-C level. Conclusion: Undaria pinnatifida soluble dietary fiber has the beneficial effect on dyslipidemia of apolipoprotein E deficient mice.
Key words: Undaria pinnatifida; Soluble dietary fiber; apolipoprotein E deficient mice
目 录
摘 要 1
关键词 1
1 前言 2
2 材料与方法 2
2.1 待检样本及试剂 2
2.2 实验动物及分组 3
2.3 血脂水平检测 3
2.4 肝脂质浓度检测 3
2.5 统计分析 3
3 结 果 3
3.1 血脂水平 3
3.2 肝脂浓度 3
4 讨 论 4
参 考 文 献 6
致 谢 7 |
